Slay the Spire 2 — Patch 106.0

Released: 5/22/2026, 12:32:27 AM

Source: https://store.steampowered.com/news/app/2868840/view/670617878982033685

Summary (AI)

Patch 106.0 for Slay the Spire 2 adjusts various cards, relics, and enemy behaviors to refine gameplay balance. Vulnerable and similar debuffs no longer decrement before extra turns granted by Pael's Eye, and several cards have been buffed or nerfed, including Fusion, Howl From Beyond, and Death March. Enemy AI and movesets have been updated, while multiple bugs related to controller navigation, language switching, and multiplayer synchronization have been fixed. Quality-of-life improvements include new animations, Bestiary additions, leaderboard enhancements, and clearer UI elements. Various relic effects and card interactions have been reworked for consistency and improved player experience.

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If an enemy has Vulnerable and a player takes an extra turn via Pael's Eye relic, the enemy's Vulnerable amount no longer decrements before the player's extra turnThis change also applies to other powers that decrement at the end of the enemy's turn (Frail, Intangible, Weak, etc.)
This change also applies to other powers that decrement at the end of the enemy's turn (Frail, Intangible, Weak, etc.)
Changed Neow's Scroll Boxes Silken Tress relics: swapped downsides and pools
Buffed Drum of Battle card: Energy gain on Exhaust effect now respects Replay and card play duplication effects like Duplicator potion
Buffed Howl From Beyond card: trigger moved from start of turn -> end of turn
Buffed Entrench card: can now gain extra Block from enchantments like Nimble
Renamed -> Scare
Changed Sealed Throne card: upgrade changed from Innate -> lowering Energy cost by 1
Now Exhausts, and loses Exhaust on upgrade
Buffed Mummified Hand relic: now randomly chooses cards in a way that's more favorable to the playerPriority 1 is cards that currently cost 1+ AND with a base cost of 1+ before any current cost modificationsPriority 2 is cards that currently cost 1+ regardless of base costPriority 3 is cards with a base cost of 1+ that have been temporarily modified to cost 0If none of these priorities match, a completely random card in the player's hand is chosen
Priority 1 is cards that currently cost 1+ AND with a base cost of 1+ before any current cost modifications
Priority 2 is cards that currently cost 1+ regardless of base cost
Priority 3 is cards with a base cost of 1+ that have been temporarily modified to cost 0
If none of these priorities match, a completely random card in the player's hand is chosen